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The extended half-life of semaglutide (approximately one week) means that effects from an overdose may persist for several days, requiring ongoing clinical vigilance

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This is when three-site rotation becomes most important

On the other hand, tirzepatide for long-term weight loss has shown similar success

Over-the-counter antidiarrheal medications like loperamide can be used judiciously for diarrhea (avoiding use if fever, blood in stool, or infection is suspected), though patients should consult their healthcare provider before regular use

Seek immediate medical attention