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Tirzepatide is a GLP-1/GIP receptor agonist that has been studied in FDA-approved medications such as Mounjaro

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2020 global estimate and projected number of adults through 2035 with an overweight BMI [1]. Obesity is a significant independent risk factor contributing to numerous chronic conditions, including diabetes, hypertension, cardiovascular disease, and obstructive sleep apnea syndrome

In this issue of Diabetologia, Maida et al

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Unrealised Expectations Despite progress, several anticipated 2025 milestones did not come to fruition: Regulatory progress stalled: FDAs obesity drug guidance, published in draft form in January 2025, remains unfinalised, whilst EMA has yet to update its 2016 guideline