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The current legal status of compounded semaglutide is significantly more restrictive

Oral Wegovy (semaglutide) has demonstrated a 15% weight-loss average in clinical trials, while Foundayo (orforglipron) has helped people lose approximately 12% to 14% of their starting weight

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Decreased suppression by insulin and increased stimulation by epinephrine

Next-generation oral medications in development aim to match injectable efficacy, which would dramatically expand the patient population willing to consider treatment