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Diabetes Obes Metab 8 , 436447, (2006)

These compounds bind to the GLP-1 receptor, a G protein-coupled receptor (GPCR) expressed mainly in pancreatic -cells, hypothalamic neurons, and peripheral tissues

GLP-1 RAs, such as semaglutide and tirzepatide, may also help improve metabolic health in patients with PCOS by promoting weight loss, improving insulin sensitivity, and reducing blood glucose levels ( 4 , 6 , 14 )

109 Identifying biomarkers that predict response to GLP-1 RAs can help customize treatment plans to maximize efficacy and minimize adverse events

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