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More recent findings confirm these effects, although effect sizes are typically small and the evidence base remains heterogeneous [96]

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Major teaching points Glucagon-like peptide-1 (GLP-1) is an important post-prandial stimulus of pancreatic insulin secretion and regulator of glucose homeostasis

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The affinity of hyperphosphorylation of tau protein to microtubules decreased, and hyperphosphorylated tau protein can no longer perform the function of maintaining the structure of the neurons, which slows the axonal transport (30)

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It was originally developed to assist individuals with type 2 diabetes in managing their blood sugar levels and continues to be used for this purpose in the UK

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