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Abstract Glucagon-like peptide-1 (GLP-1) and its receptor agonists (GLP-1RAs) are well-established therapies for metabolic conditions such as type 2 diabetes and obesity due to their ability to enhance insulin secretion, promote weight loss, and regulate blood glucose levels

They target narrow pathways and often lose effectiveness quickly

Adherence to weekly or twice-weekly injection schedules is essential

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The skin should be clean, dry, and free from cuts, irritation, rashes, or excessive hair