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Genome-wide identification of GLP-1 NotchLAG-1 CSL transcriptional targets: ChIP-seq lst-1 and sygl-1 , which were identified in a small candidate gene RNAi screen, are GLP-1 transcriptional targets that are redundantly required for the germline stem cell fate [20,21,42] ( Introduction )

Slower GLP-1 titration schedules and optimized nutrition also reduce metabolic stress

GLP-1 and weight loss: Unraveling the diverse neural circuitry

Look AHEAD Research Group

This is not weakness

Rather than targeting individual diseases, an emerging strategy is to repurpose existing medications that may act on these underlying aging processes