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The National Weight Control Registry, which tracks individuals who have successfully maintained significant weight loss, identifies common characteristics including high levels of physical activity, regular breakfast consumption, consistent eating patterns across weekdays and weekends, and frequent self-weighing

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The mechanisms underlying these results are based on the activity of GLP-1 in controlling eating, acting on satiety signals [92] in areas of the brain involved in food intake regulation [93] and peripheral action, reducing gastric emptying and intestinal motility, and slowing absorption [94]