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When probiotics ferment inulin, they produce short-chain fatty acids like butyrate, which are directly linked to GLP-1 release

doi: 10.1210/endrev/bnac018

Among patients with available prescription data (n = 14), semaglutide was most commonly initiated at 0.25 mg or 0.5 mg weekly

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Another promising direction involves mucoadhesive nanocarriers that anchor to intestinal epithelium and release GLP-1 analogs in a site-specific manner, minimizing systemic degradation [35]