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In the context of withdrawal symptoms (Fig 1B-E), the heroin natural withdrawal group (H) exhibited a statistically significant reduction in the number of standing positions compared to the saline control group (S) (t (14) =3.331, P = 0.005, Fig 1B)

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In the U.S., according to data collected between 2015 and 2018, the average weight of adult men aged 20 and older is 199.8 pounds