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When you begin using a GLP-1 (glucagon-like peptide-1) receptor agonist like semaglutide, you might find yourself paying closer attention to every small change in your body

Later, Lotte Knudsen and her team created analogues of human GLP1

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STEP-4 gave every participant a 20-week course of semaglutide 2.4 mg once weekly, and produced a mean weight loss of 10.6%, before randomisation to either continued semaglutide treatment or exchange to placebo for an additional 48 weeks