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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Long-term testosterone therapy in hypogonadal men ameliorates elements of the metabolic syndrome: an observational, long-term registry study

When the container is three-quarters full, seal it and dispose according to local regulations

Weve uncovered a divide between the way patients perceive GLP-1s as a short-term fix and the clinical science behind how GLP-1s work

There is a third path

Indeed endocannabinoid signaling through CB1R regulates the activity of dopamine (DA) neurons in the VTA [52], which projects to the nucleus accumbens, a key brain reward region activated by addictive drugs including THC [53, 54]

Another ongoing trial will also investigate the effects of tirzepatide on CKD in patients with or without T2D, with a primary outcome of change in kidney oxygenation (TREASURE-CKD, NCT05536804) [71]
