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Pain at injection site semaglutide is a recognized local adverse reaction affecting approximately 1.2-1.4% of patients using this GLP-1 receptor agonist for type 2 diabetes or weight management

Chew thoroughly: Digestion starts in the mouth

Outcomes assessed at initiation, six months and discontinuation or last consultation included HS-PGA, flare frequency, Numerical Rating Scale (NRS) for pain and suppuration, Dermatology Life Quality Index (DLQI) and body mass index (BMI)

Second, clean your injection site with an alcohol pad and let it dry completely

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It usually settles on its own once weight stabilises and nutrition improves