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Toxicity, Efficacy, and Safety Since tirzepatide has a relatively long half-life, patients who overdose on the medication should undergo prolonged monitoring

When the medication becomes less potent, it may deliver a lower dose than intended, making treatment less effective

Psychological resistance disappears almost entirely for most people

This weight gain results from decreased metabolic rate and may be challenging to address with lifestyle interventions alone, even with thyroid hormone replacement therapy

[2] While there is no specific prohibition against combining them, the absence of formal guidance does not automatically mean the combination is safe or advisable for everyone

Within the treated group, inflammation markers ESR and CRP dropped , along with LDL and triglycerides