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Mechanism of Action Semaglutide is a GLP-1 receptor agonist, a class of medication that mimics the action of the glucagon-like peptide-1 (GLP-1) hormone

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This dual action mechanism enhances insulin secretion, reduces glucagon levels, and slows gastric emptying, leading to improved glycemic control and significant weight loss

The agency attributed the high demand to a surge in off-label usemeaning the drug is prescribed for purposes other than its registered indication

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