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Most prescribers fill this gap with clinical judgment based on the known pharmacology of both substances

For example, SNPs within T1R1 and T1R3 , which encode for sweet and umami receptors, have been associated with the loss of monosodium glutamate taste [100]

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Diabetes Obes Metab 13(5):426433 Becker RHA, Stechl J, Steinstraesser A, Golor G, Pellissier F (2015) Lixisenatide reduces postprandial hyperglycaemia via gastrostatic and insulinotropic effects