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The development of rare adverse events, which may not occur until a patient has been on a drug for a number of years, is of concern, but until more patients are followed for an adequate period of time, the true safety of a drug cannot be stated or concluded

GLP-1 patients in the dataset had an even higher risk if they were younger, male, had smoked in the past, and had a marked decrease in their A1C levels
[3] Higher adherence and satisfaction

In addition, regular physical activity is associated with reduced risk of microvascular complications, osteoporosis and cancer in people with type 1 diabetes [148]

In high-dose macrodosing, side effects like vomiting or diarrhea are common
