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In 2025, obesity remains one of the most critical health crises in the United States, affecting more than 40 percent of U.S

Other studies have suggested that there is no significant difference in the risk of acute pancreatitis or pancreatic cancer between the two groups when GLP-1RA is used (84, 85)

However, the results were presented to both the expert panel and in the manuscript according to study design, outcome measurement, and the quality of outcome reporting

Back to Journals Drug Design, Development and Therapy Volume 13 The development of an oral GLP-1 receptor agonist for the management of type 2 diabetes: evidence to date Authors Antza C , Nirantharakumar K , Doundoulakis I, Tahrani AA, Toulis KA Received 31 October 2018 Accepted for publication 27 June 2019 Published 22 August 2019 Volume 2019:13 Pages 29852996 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Tuo Deng Christina Antza, 1,* Krishnarajah Nirantharakumar, 2,* Ioannis Doundoulakis, 3 Abd A Tahrani, 46 Konstantinos A Toulis 2, 3 1 3rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University, Thessaloniki, Greece