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Additionally, it should not be used if a patient has an ongoing gallbladder inflammation, severe pain or burning sensation in the stomach area, difficulty breathing, poor gastrointestinal tolerability to semaglutide (the main active ingredient of Wegovy), severe nausea, and other symptoms occurring in response to GLP 1 receptor agonists

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In 2018, the country spent $13.7bn on GLP-1 drugs

For diabetes management, dose adjustments are guided by glycemic control markers, primarily HbA1c and self-monitored blood glucose readings

Figure 1 shows some of their effects

This work suggests that we may have overlooked a third phase, perhaps the most challenging one: maintaining the result over the long term