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these events were generally mild to moderate, the majority resolved during treatment, and most participants continued taking retatrutide

Although CVC treatment failed to meet its primary endpoint in the Phase 2b CENTAUR study (ClinicalTrials.gov NCT02217475) defined as histological improvement in NAS without worsening of fibrosis, 19 it did improve levels of measurable liver fibrosis without worsening NASH

Endocrinology (2008) 149(6):316775

Clinical trials help set realistic expectations, which is essential when discussing treatment goals

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