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280 Correspondingly, human studies demonstrate improvements in executive function, memory, and attention, likely mediated through enhanced cerebrovascular integrity and decreased neuroinflammation

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Chronic unpredictable stress, considered a model of depression, results in a reduction in dendritic lengths and branching of apical dendrites, the loss of functional synaptic spines, and the reduction of dendritic complexity in PFC neurons and in the hippocampal CA3 pyramidal neuronal cell layer (McEwen et al., 2012

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