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Under a treatment duration of 24.3 18.9 months (range 6 to 51), metabolic parameters also improved [homeostatic model assessment of insulin resistance 3.2 3.5 (range 9.1 to 0.8)

While this is not a comprehensive review of genetic predispositions for potential psychiatric side effects following GLP-1 signaling, it highlights the importance of future research to better understand individual factors that could contribute to conditions such as depression, anxiety, and suicidal ideation following GLP-1 use

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