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The one oral option (semaglutide/Rybelsus) has specific instructions: take on an empty stomach with a small amount of water and wait before eating or taking other medications to ensure absorption

oral formulation (Rybelsus) also available Lixisenatide (Lyxumia) once-daily injection NICE guidance for type 2 diabetes (NG28) recommends GLP-1 receptor agonists in specific circumstances: typically as a third-line option when other treatments haven't achieved adequate glycaemic control, particularly in people with a BMI 35 kg/m (adjusted for ethnicity), or for whom weight loss would benefit other obesity-related comorbidities, or for whom insulin would have significant occupational implications

Eggs are the baseline

Inject slowly over 5 to 10 seconds rather than pushing the plunger in quickly

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10.1038/s42255-023-00812-z 98 OforiJ