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Women face additional layers of complexity

PPAR-: peroxisome proliferator-activated receptor gamma

JCEM Case Reports

Given the potent actions of metformin on [1] suppression of hepatic glucose production and [2] peripheral glucose disposal, it is not surprising that elimination of incretin receptor signalling fails to eliminate the salutary effects of metformin on oral glucose tolerance in normal mice or mice on a high-fat diet

This can happen with any form of rapid weight loss, whether through medication, surgery, or intensive lifestyle changes

Remember that most people taking GLP-1 medications experience no vision problems , particularly when appropriate monitoring and gradual glycaemic improvement are implemented