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doi: 10.1523/JNEUROSCI.5855-12.2013 104 KnightR.CallewaertC.MarotzC.HydeE
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Patients achieved substantial weight loss during the initial GLP-1 RA phase (~1822% at 12 months), which was subsequently maintained after its discontinuation, with total weight reduction reaching 25.5% (95% CI 23.127.9%) at 593 days, with most patients on metformin

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Industry projections hint at potential availability by 2028, contingent on Retatrutide FDA approval processes

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Tesamorelin preferentially reduces visceral fat without significantly affecting subcutaneous fat
