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Furthermore, these therapies have been shown to reduce the activation of microglial cells, key immune cells that play a significant role in triggering chronic pain in the central nervous system [36]

Tirzepatide (Mounjaro) Tirzepatide is unique because it targets two hormones: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)

Originally designed to treat diabetes, these injectable medicationslike Ozempic and Wegovyhave gained a reputation as the weight-loss secret behind some of the most jaw-dropping transformations in the spotlight

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Oral GLP-1 RA in Development The success of orally administered semaglutide in clinical trials has led to the development of other oral formulations

Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the SURMOUNT-4 Randomized Clinical Trial