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Compared with SGLT2i alone, combination therapy was significantly associated with 42% lower risk of ischemic stroke, 37% lower risk of MI, 46% lower risk of 3-point MACE, and 45% lower risk of 5-point MACE among people with T2D and ASCVD

For humans, the model-predicted median clearance (CL) and volume of distribution (Vss) of semaglutide were 0.0397 L/h and 6.23 L, respectively

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Using this atlas we find that multiple neuronal cell types involved in the processing of aversive stimuli and nausea had higher GLP1R expression in females than males

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