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Dosing progression Both medications start at low doses and gradually increase

Participants were randomized to receive weekly subcutaneous doses of retatrutide (1 mg, 4 mg, 8 mg, or 12 mg) or placebo for 48 weeks

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Drucker DJ

Patients currently taking metformin who are considering compounded semaglutide options, injectable or oral semaglutide forms, should maintain open communication with their healthcare providers about their treatment goals and any concerns

Additionally, Ozempic should not be used by individuals with known allergies to any of its ingredients

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