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Researchers have also noted that 70% of diabetes patients discontinue GLP-1 receptor agonist treatment within two years, limiting the long-term efficacy of these drugs

2015 Feb;26(2):589-99

Weill Cornell News
Holst, et al (2011)

Doctors usually begin with a low dose of semaglutide, such as 0.25 mg, given once a week as a subcutaneous injection

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