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New England Journal of Medicine, 389 (24), 22212232

By activating the GLP-1 receptor, Ozempic causes your pancreas to produce more insulin while reducing the amount of glucagon that is released

Even then, approval often involves 2-4 month delays and step-therapy requirements

Instead, it experiences a rebound surge in ghrelin, the 'hunger hormone,' making you feel significantly hungrier than before starting therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Mosterd C.M., Bjornstad P., van Raalte D.H
