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2 GLP-1 receptors are expressed in brain regions involved in satiation, satiety, and reward, including the hypothalamus, brainstem, and mesolimbic pathways

The injectable formulations are administered once weekly via subcutaneous injection, meaning the medication is delivered into the fatty tissue layer beneath the skin rather than into muscle or directly into the bloodstream

However, patients should consult their GP or pharmacist before using these preparations , and they should not be used if there is blood in the stool, high fever, or severe abdominal pain

Charrier JA, Martin RJ, McCutcheon KL, Raggio AM, Goldsmith F, Goita M, et al

GLP-1 is part of the signalling pathway that tells your body you have eaten, and prepare it to use the energy that comes from your food

Check your prescription coverage If you have insurance, check the drug formulary (list of covered drugs) or contact your insurance provider to verify if Wegovy is covered for your prescribed diagnosis