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Precedence Research
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Gut hormones like ghrelin ( hunger) & GLP-1/PYY ( hunger) signal to the hypothalamus' arcuate nucleus
This process keeps food in the digestive system for longer making people feel fuller for longer, thus reducing appetite and inducing weight loss
Animals deficient for the GCG gene in the intestine, still experience a normal incretin effect disrupted with the GLP-1R antagonist Exendin (9-39) (204)
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity
