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Additional research is necessary to examine fracture reduction independent of weight loss. This research may also mainly pave the way for more research, rather than giving definite answers

For comparison, nausea has been reported at approximately 44% in the Wegovy semaglutide trials and 28% in the Zepbound tirzepatide trials

Weight loss with semaglutide has become more popular than ever, as it turns a failed attempt at weight loss into a potentially successful one

Short half-life, pleiotropy, and behavioral or cardiovascular effects were historically interpreted as disqualifying features
Health experts say more research is needed to understand the connection
