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Furthermore, an improvement in NAS was observed in 83% of patients treated with semaglutide 0.4 mg/day, 80% of those treated with 0.2 mg/day, 71% of those treated with 0.1 mg/day and only 44% of those treated with placebo
[7] Common side effects include low blood sugar, nausea, dizziness, abdominal pain, and pain at the site of injection
The AWARD-1 study showed that dulaglutide had slightly greater efficacy for HbA 1c reduction than twice-daily exenatide (-1.5% [-17mmol/mol] vs -1% [-11mmol/mol]), but led to similar weight loss (about 1 to 2 kg)
The combination also preserved muscle function and improved insulin sensitivity , which indicates potential benefits of combination therapy
10.1111/jdi.12749 57 PfefferM
