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This means it does not make assumptions about anyones health, worth, fitness or ability based on body size

Furthermore, patients experiencing frequent hypoglycemia, poor glycemic control on current insulin regimens, or those using complex treatment strategiessuch as multiple daily injectionsmay benefit from a switch to a simplified regimen with combination basal insulin and GLP-1 agonists [36]

Assessment of efficacy and tolerability of once-daily extended release metformin in patients with type 2 diabetes mellitus

Thats the paradox this review sits inside
N., Gao, G., Bisello, A

DM is also a frequent condition in the general population