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Background Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have emerged as breakthrough weight loss agents

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has today approved a new indication for Wegovy (semaglutide) to reduce the risk of overweight and obese adults suffering serious heart problems or strokes.

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Clinical trials of FDA-approved tirzepatide products have shown weight-related effects in some participants when used alongside diet and lifestyle changes