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However, in the exenatide treatment group, the primary outcome rate was 61.2% (n=170), compared to 56.7% in the standard treatment group (n=171), with an adjusted ratio of 1.22 [95% CI, 0.79-1.88] (P=0.38)., which meant that the proportion of subjects who achieved the desired effect in exenatide treatment group was higher (110)

Clinical judgement and individualised assessment are essential when considering any pharmacological intervention

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Its not clear whether the same effect occurs in humans, and large reviews of human data from 2024 to 2025 have not shown an increased risk, but the family-history exclusion remains in place across all GLP-1 SmPCs