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Although they both work in similar ways, Wegovy and Mounjaro are still different medications with different mechanisms and active ingredients

Glucagon receptor activation causes more gastrointestinal distress than GIP activation, which partly explains why survodutide has higher discontinuation rates in clinical trials compared to tirzepatide

GIP is short for glucose-dependent insulinotropic polypeptide.) These two naturally occurring hormones help the body increase energy expenditure and regulate blood glucose levels and appetite, all contributing to weight loss

DOI: 10.1038/s41591-023-02672-2

Therapeutic management is divided into two kinds of measures: Lifestyle intervention and pharmacological/surgical treatment