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By the second month of treatment, those in the semaglutide group had reduced the quantify of alcohol consumed on drinking days by an average of nearly 30%, compared to an average reduction of about 2% in the placebo group

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The GLP1R weight loss finding from the main study did not replicate in the UK Biobank, though the authors note that the UK Biobank group was too small to reliably detect the effect

doi: 10.1152/ajpgi.00024.2010 [DOI] [PubMed] [Google Scholar] 15