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GLP-1 agonists are large peptide molecules

Submit a New Drug Application (NDA): Eli Lilly is expected to submit a New Drug Application (NDA) to the FDA for obesity if the Phase III program is successful

Phentermine has been FDA-approved since 1959 and has one of the longest safety records of any weight loss medication

Most patients in the control group received other GLP-1 drugs such as semaglutide, which Novo Nordisk sells for diabetes as Ozempic or Rybelsus, or Lilly's Trulicity (dulaglutide)

PMID 35133415
