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Confounding effects from the concurrent use of medications such as antidepressants or benzodiazepines also complicate interpretation, making it difficult to attribute observed outcomes specifically to GLP1RA exposure

Keywords: type 2 diabetes, incretins, glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide Introduction: The Incretin Effect in Health and Disease The gastrointestinal system has an intricate pathway of hormones that are released from the gut lining upon ingestion of food and regulate glucose metabolism and appetite

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The aim of this narrative review is to explore the therapeutic potential of GLP-1RAs in the management of OSA, by summarizing available preclinical and clinical evidence on their efficacy, mechanisms, and potential impact on OSA comorbidities

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Our Ozempic and Wegovy comparison explains those brands and their approved uses in more detail