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Tirzepatide (Zepbound) - FDA Approved 2023: According to clinical trials cited by multiple sources including NBC News, tirzepatide (a GIP/GLP-1 dual agonist) showed approximately 21% to 22.5% mean weight loss on its highest dose after 72 weeks, compared to approximately 3% for placebo

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These studies emphasize the indispensable role of gut microbiota in regulating gut motility

Neuropharmacology 62: 19161927, 2012

This drop-off may be attributed to a subset of patientsoften impulse buyersseeking rapid weight loss rather than committing to long-term therapeutic regimens

Fitness should matter more to people using these products for weight loss, and this underscores the need for more education on the importance of preserving fitness while losing weight