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Semaglutide: the GLP-1 receptor agonist backbone Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, an acylated analog of the native incretin hormone GLP-1

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doi: 10.1016/j.diabres.2004.02.004

If there isn't a significant change, we discontinue the medication, she says

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This medication enhances glucose-dependent insulin secretion from pancreatic beta cells, meaning it stimulates insulin release only when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia compared to some other diabetes medications