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A potential drawback is that any injection-site soreness or mild swelling might be noticeable overnight when you're lying down, though this rarely causes problems

The ideal candidate profile for favourable safety outcomes looks something like this: generally good baseline health, no history of pancreatitis or thyroid cancer, no active GI conditions, not pregnant or planning to become pregnant, not using multiple glucose-lowering medications simultaneously, and willing to follow a genuine slow-escalation protocol rather than rushing to maximum dose

Aim for steady, sustainable progress of 1-2 pounds per week, celebrating small victories while maintaining focus on your overall weight management goals