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Additionally, smoking causes a state of chronic inflammation

A significant reduction in alcohol intake was observed at follow-up compared with baseline, including among adults who were considered high alcohol consumers and drank more than 11 U alcohol per week at the start of the study

Meal schedule dependent experiment Based on the results, we selected the 1 g/kg dose of Ex which reduced food intake without observable side effects, and went on to investigate the hypothesised meal schedule dependent effects of Ex in all four possible meal schedule conditions (see Fig

S2 and S3, respectively

Current medications, including over-the-counter supplements and vitamins

Months 4 through 12 represent the sustained weight loss phase where most people achieve their maximum results