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A Phase III, 26-week, randomized, double-blinded, placebo-controlled trial, the PIONEER 1, exploring the oral form of semaglutide at 3-mg, 7-mg and 14-mg doses in patients with T2DM is currently ongoing and it is soon expected to be concluded

Moreover, drug-induced lupus (DIL), with clinical manifestations similar to SLE, is an autoimmune phenomenon caused by exposure to certain drugs [287]

GLP-1 receptor agonists in psychiatry: a pharmacoepidemiological scoping review

While our findings support the potential of GLP-1RAs in improving cognitive function, there is a need for further clinical investigations to validate these mechanisms and to explore the long-term effects of GLP-1-based therapies in human populations

Remarkably, insulin-producing islet cells responded to N-terminally truncated forms of GLP-1, exhibiting increased levels of cyclic AMP accumulation within minutes of exposure to 50 pM5 nM GLP-1(7-37) (Figure 4A)