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Statistics Data are presented as mean SEM

GLP-1 GIP( ), ( ) ,

Search strategy The resources were extracted from the PubMed database, in April 2021, using the keywords of (GLP-1 OR Glucagon-like peptide-1 OR GLP-1RA) AND (SARS-CoV-2 OR COVID-19 OR novel coronavirus) AND (inflammation OR anti-inflammatory OR cytokine storm)

If youre taking Ozempic, Wegovy, or Mounjaro and suddenly struggling to go to the bathroom, youre not imagining it and youre definitely not alone

Each receptor it activates produces a distinct effect: GLP-1 receptor: suppresses appetite and slows digestion, reducing overall caloric intake GIP receptor: increases insulin sensitivity, supporting better glycemic control Glucagon receptor: boosts fat metabolism, driving energy expenditure independent of diet These three pathways point toward two outcomes: meaningful weight loss and improved glycemic control

Future developments may enable more personalised approaches to weight loss injection therapy, improving both tolerability and outcomes for patients requiring pharmacological support for obesity management within the UK healthcare system