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Combining it with other weight loss medications may enhance outcomes but also poses increased risks of adverse reactions and drug interactions

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Nat Commun 15:4548 Wharton S, Calanna S, Davies M et al (2022) Gastrointestinal tolerability of once-weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between Gastrointestinal adverse events and weight loss

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