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You should rotate injection sites with each weekly dose, avoiding the exact same spot for consecutive injections

Tan Q, Akindehin SE, Orsso CE, Waldner RC, DiMarchi RD, Mller TD, Haqq AM

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If nausea remains problematic despite conservative management strategies, healthcare providers may consider maintaining a lower dose for an extended period before further escalation, or in some cases, temporarily reducing the dose

Larger volumes take longer to inject, require more space in the subcutaneous tissue, and may produce a more noticeable lump immediately after injection