what is glp 1 microdosing GLP-1s: Does It Work? Risks and Benefits Microdosing Tirzepatide and Semaglutide for

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Discussion The results of the current meta-analysis, that included 60,080 patients with T2DM, 14,804 of whom without established CV disease, demonstrate that GLP-1RA reduce the risk of MACE by 14% in the overall diabetic population, with an apparently greater effect in patients with known CV disease as compared with those without established CV disease (16% vs 6% reduction, respectively)

However, there's caution due to competitive risks and potential US policy headwinds

Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, et al

Additional evidence comes from a randomized controlled trial by Naing et al., which tested a structured insulin tapering protocol in patients with poorly controlled T2DM on multiple daily insulin injections

A new systematic review of preclinical studies found that GLP-1 drugs may reduce key Alzheimers markers like amyloid beta and tau protein